TY - JOUR AU - Manzhalii , Еліна PY - 2021/12/14 Y2 - 2024/03/29 TI - HEPATORENAL SYNDROME. DIFFERENTIATED APPROACH TO TREATMENT JF - Actual Problems of Nephrology JA - APN VL - IS - 29 SE - Articles DO - 10.37321/nefrology.2021.29-02 UR - https://apn.org.ua/index.php/journal/article/view/37 SP - 21-28 AB - <p>Introduction. The choice of treatment tactics and the study of the pathogenesis of HRS as a pathological condition of the disease is important to prevent the development of complications in all body systems. After all, HRS as a syndrome manifests itself as a direct lesion on the excretory system, in particular on the kidneys, and with a further risk of developing renal failure. Patients with chronic liver diseases are especially sensitive to the occurrence of HRS.<br>Goal. Analyze the causal relationship of the occurrence and development of HRS and generalize the treatment strategy based on evidence-based medicine.<br>Materials and methods. Bibliographic – a theoretical analysis is carried out and a generalization of literature data is carried out. Description and analysis were used in the research.<br>Results and its discussion. Scientists differentiate the main criteria for GDS as follows. Serum creatinine levels greater than 133 μmol / L; there is no decrease in serum creatinine levels below 133 μmol / l after a twoday discontinuation of diuretics against the background of albumin infusion therapy (the recommended dose of albumin is 1 g / kg of body weight per day to a maximum of 100 g / day); the absence of other reasons for the development of renal failure: shock, sepsis, multiple organ failure, hypovolemia due to extrarenal losses, the use of nephrotoxic agents; absence of parenchymal kidney diseases, manifested by proteinuria more than 500 mg / day, microhematuria (more than 50 erythrocytes in the field of view) and / or changes in the structure and vascular architectonics of the kidneys on ultrasound; the presence of CB with ascites [12].<br>Conclusions. Monitoring the patient’s indicators, prescribing treatment tactics depending on the type of HRS makes it possible to stabilize the patient’s condition.</p> ER -